Plant layout should be designed that it should be easy to clean, maintain and operate.
Design and layout of premises is so that it prevents entry of insects, pests, birds, vermins and rodents in the premises.
Manufacturing unit should not be as far, it create labor and staff availability problem. Extreme climate change like heavy rain, temperature, humidity, earth quake should be considered while selecting location for pharma plant etc.
According to Schedule-M of Drug and Cosmetic Act & Rules, “The factory building(s) for manufacture of drugs shall be so situated and shall have such measures as to avoid risk of contamination from external environment including open sewage, drain, public lavatory or any factory which produces disagreeable or obnoxious, odour, fumes, excessive soot, dust, smoke, chemical or biological emissions.” Land, Building and Premises: Investment for land and Building may depend at many factors like location, area, state, material used etc. At prime location cost of plant may be much higher side where as at backward area, it may be less.
Pharmaceutical manufacturing unit requires technical skill to set-up.
If you want to check list of documentations that are necessary for starting pharma manufacturing company read at out article: How to start pharmaceutical manufacturing Unit?
Ground Floor: Raw material Storage room, Packaging Material Storage Room, Finished Goods Storage room, dispensing and weighing section, Changing Rooms for staff and workers, visitor room etc is best suitable sections for ground floor. Each raw material should be well labeled and testes, under test, rejected, approved raw material should be placed separately.
First Floor: First floor is best suitable for all manufacturing processes.
In pharmaceutical, we need to get approval from Drug Department before starting manufacturing of any dosage form.
According to Schedule M of Drug and Cosmetic Act, “The building(s) used for the factory shall be designed, constructed, adapted and maintained to suit the manufacturing operations so as to permit production of drugs under hygienic conditions.